SCHEMBL25818246

SCHEMBL25818246

c1ccc(-n2c(-c3ccc4c(c3)-c3c(c5ccccc5c5sc6ccccc6c35)C43C4CC5CC(C4)CC3C5)nc3ccccc32)cc1

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
PTGER4 P35408 1/20 0.31
MAPK10 P53779 2/20 0.31
RECQL P46063 1/20 0.31
GRIA1 P42261 1/20 0.30
CACNG8 Q8WXS5 1/20 0.30
CACNG2 Q9Y698 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25037666 0.77 MAPK10 (0.39) HDAC1HDAC8HDAC6ESR1ESR2
SCHEMBL25878595 0.75 RECQL (0.34) ESR1ESR2RECQL
SCHEMBL25038412 0.74 MAPK10 (0.38) HDAC1HDAC8HDAC6ESR1ESR2
SCHEMBL25878792 0.74 ESR1 (0.31) ESR1ESR2
SCHEMBL25878600 0.74 ESR1 (0.33) HDAC1HDAC8HDAC6ESR1ESR2
SCHEMBL25817940 0.72 RECQL (0.36) HDAC1HDAC8HDAC6ESR1ESR2
SCHEMBL23625981 0.71 PTGER4 (0.39) HDAC1HDAC8HDAC6ESR1ESR2
SCHEMBL461927 0.71 ESR1 (0.46) HDAC1HDAC8HDAC6ESR1ESR2
SCHEMBL29362982 0.71 ESR1 (0.46) HDAC1HDAC8HDAC6ESR1ESR2
SCHEMBL29647854 0.71 ESR1 (0.46) HDAC1HDAC8HDAC6ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230217825-A1 ORGANIC COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE USING SAME SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-07-06 US disclosed
US-20230217825-A1 ORGANIC COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE USING SAME SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230217825-A1 ORGANIC COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE USING SAME OR10J3, AOC2, EPCAM HDAC1 2896/4885HDAC8 3470/4885HDAC6 4278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.