Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 9/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.33 |
| ▸ | SKP1 | P63208 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29030594 | 0.83 | GRIN2B (0.44) | GRIN2BADORA2AADORA2BCYP3A4CYP2D6 | |
| SCHEMBL25818351 | 0.83 | NPC1 (0.35) | GRIN2BADORA2AADORA2BCARM1PRMT6 | |
| SCHEMBL25256028 | 0.80 | GRIN2B (0.65) | GRIN2BCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL31025943 | 0.80 | GRIN2B (0.65) | GRIN2BCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL25255284 | 0.78 | KDM4E (0.48) | GRIN2BADORA2AADORA2BKDM4E | |
| SCHEMBL31270846 | 0.78 | KDM4E (0.48) | GRIN2BADORA2AADORA2BKDM4E | |
| SCHEMBL25818890 | 0.74 | KCNH3 (0.41) | ADORA2AADORA2BVNN1 | |
| SCHEMBL31270725 | 0.74 | KCNH3 (0.41) | ADORA2AADORA2BVNN1 | |
| SCHEMBL25424339 | 0.73 | ALDH1A1 (0.38) | ADORA2AADORA2BALDH1A1 | |
| SCHEMBL25818353 | 0.71 | PDE4A (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125121-A1 | TRICYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |