Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 11/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 11/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25818358 | 0.92 | TLR7 (0.38) | AGTR1AGTR2TLR7TLR8P2RX3 | |
| SCHEMBL25818353 | 0.88 | PDE4A (0.42) | AGTR1AGTR2TLR7TLR8 | |
| SCHEMBL25255536 | 0.85 | TLR7 (0.36) | AGTR1AGTR2TLR7TLR8P2RX3 | |
| SCHEMBL26664986 | 0.84 | GRIN2B (0.41) | TLR7P2RX3 | |
| SCHEMBL25819006 | 0.81 | GLS (0.39) | — | |
| SCHEMBL31270623 | 0.81 | GLS (0.39) | — | |
| SCHEMBL25818360 | 0.79 | TLR7 (0.36) | AGTR1AGTR2TLR7TLR8P2RX3 | |
| SCHEMBL30484360 | 0.79 | TLR7 (0.37) | TLR7TLR8 | |
| SCHEMBL25301816 | 0.79 | TLR7 (0.48) | TLR7TLR8 | |
| SCHEMBL25818361 | 0.78 | TLR7 (0.52) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125121-A1 | TRICYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |