Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 5/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25818813 | 0.88 | PDE4A (0.39) | TLR7TLR8AGTR1AGTR2CNR2 | |
| SCHEMBL25818358 | 0.86 | TLR7 (0.38) | TLR7P2RX3TLR8AGTR1AGTR2 | |
| SCHEMBL25818361 | 0.81 | TLR7 (0.52) | TLR7TLR8 | |
| SCHEMBL25819010 | 0.81 | GLS (0.38) | P2RX3 | |
| SCHEMBL25818355 | 0.79 | AGTR1 (0.37) | TLR7P2RX3TLR8AGTR1AGTR2 | |
| SCHEMBL25818353 | 0.79 | PDE4A (0.42) | TLR7TLR8AGTR1AGTR2 | |
| SCHEMBL25303740 | 0.77 | P2RX3 (0.43) | P2RX3 | |
| SCHEMBL25818814 | 0.74 | TLR7 (0.53) | TLR7TLR8 | |
| SCHEMBL25260616 | 0.73 | RORC (0.37) | P2RX3 | |
| SCHEMBL25819220 | 0.73 | GLS (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125121-A1 | TRICYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |