Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31270623 | 1.00 | GLS (0.39) | GLSFAAHPIK3CAPRKDCRORC | |
| SCHEMBL25262168 | 0.91 | ADORA2B (0.41) | GLSFAAHPIK3CAPRKDCRORC | |
| SCHEMBL31270748 | 0.91 | ADORA2B (0.41) | GLSFAAHPIK3CAPRKDCRORC | |
| SCHEMBL25255536 | 0.88 | TLR7 (0.36) | — | |
| SCHEMBL31270644 | 0.86 | ADORA2A (0.41) | GLSFAAHPIK3CAPRKDCGPR119 | |
| SCHEMBL25256593 | 0.86 | ADORA2A (0.41) | GLSFAAHPIK3CAPRKDCGPR119 | |
| SCHEMBL26664986 | 0.86 | GRIN2B (0.41) | FAAHSMN1; SMN2 | |
| SCHEMBL25819220 | 0.85 | GLS (0.37) | GLSFAAHRORCIDO1TDO2 | |
| SCHEMBL25301552 | 0.85 | RORC (0.37) | GLSPIK3CAPRKDCRORCGPR119 | |
| SCHEMBL25296505 | 0.84 | GLS (0.38) | GLSRORCIDO1TDO2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125121-A1 | TRICYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |