SCHEMBL25818456

SCHEMBL25818456

Clc1nc(-c2cccc(-c3ccc4cccc(-c5ccccc5)c4c3)c2)nc(-c2cccc3c2oc2ccccc23)n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.42
PIM1 P11309 1/20 0.38
CSNK2A2 P19784 1/20 0.38
CSNK2B P67870 1/20 0.38
PIM3 Q86V86 1/20 0.38
PIM2 Q9P1W9 1/20 0.38
PLA2G2A P14555 2/20 0.36
PLA2G4A P47712 2/20 0.36
PLA2G10 O15496 1/20 0.36
ALDH1A1 P00352 5/20 0.35
KDM4E B2RXH2 4/20 0.35
HSD17B10 Q99714 3/20 0.35
ATM Q13315 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C19 P33261 1/20 0.35
RAB9A P51151 1/20 0.35
GGPS1 O95749 1/20 0.35
MAPT P10636 5/20 0.34
HPGD P15428 3/20 0.34
TSHR P16473 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25817754 0.93 ALOX5 (0.45) ALOX5PIM1CSNK2A2CSNK2BPIM3
SCHEMBL25818523 0.92 PLA2G2A (0.40) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL21128856 0.91 ALOX5 (0.44) ALOX5PIM1CSNK2A2CSNK2BPIM3
SCHEMBL25818466 0.90 ALOX5 (0.43) ALOX5PIM1CSNK2A2CSNK2BPIM3
SCHEMBL29739107 0.90 ALOX5 (0.44) ALOX5PIM1CSNK2A2CSNK2BPIM3
SCHEMBL27098254 0.89 ALOX5 (0.42) ALOX5PIM1CSNK2A2CSNK2BPIM3
SCHEMBL22889388 0.89 ALOX5 (0.43) ALOX5PIM1CSNK2A2CSNK2BPIM3
SCHEMBL22889403 0.89 ALOX5 (0.45) ALOX5PIM1CSNK2A2CSNK2BPIM3
SCHEMBL22888615 0.89 ALOX5 (0.45) ALOX5PIM1CSNK2A2CSNK2BPIM3
SCHEMBL25818407 0.88 PIM1 (0.43) ALOX5PIM1CSNK2A2CSNK2BPIM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230225206-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2023-07-13 US disclosed
US-20230225206-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2023-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230225206-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF NFE2L2, ESR1, OR51E2 ALOX5 556/4885PIM1 2802/4885CSNK2A2 2565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.