Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.65 |
| ▸ | NOS3 | P29474 | 5/20 | 0.50 |
| ▸ | NOS1 | P29475 | 5/20 | 0.50 |
| ▸ | NOS2 | P35228 | 3/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25818515 | 0.91 | ALDH1A1 (0.54) | ALDH1A1KDM4ELMNAMAPTPTK2B | |
| SCHEMBL188501 | 0.83 | ALDH1A1 (0.63) | ALDH1A1KDM4ELMNAMAPTPTK2B | |
| SCHEMBL14016156 | 0.83 | MAPT (0.63) | ALDH1A1KDM4ELMNAMAPTPTK2B | |
| SCHEMBL16479227 | 0.82 | ALDH1A1 (0.49) | ALDH1A1KDM4ELMNAMAPTPTK2B | |
| SCHEMBL4572836 | 0.81 | NOTUM (0.47) | ALDH1A1KDM4ELMNAMAPTPTK2B | |
| SCHEMBL24109783 | 0.81 | KDM4E (0.60) | ALDH1A1KDM4ELMNAMAPTPTK2B | |
| SCHEMBL22860674 | 0.80 | KDM4E (0.48) | ALDH1A1KDM4ELMNAMAPTPTK2B | |
| SCHEMBL21208732 | 0.79 | NOTUM (0.46) | ALDH1A1KDM4ELMNAMAPTPTK2B | |
| SCHEMBL7680979 | 0.79 | ALDH1A1 (1.00) | ALDH1A1KDM4ELMNAMAPTPTK2B | |
| SCHEMBL3437431 | 0.78 | NOTUM (0.51) | ALDH1A1KDM4ENOTUMCHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219969-A1 | ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219969-A1 | ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF | GAP43, SLC18A2, PNMT | ALDH1A1 1852/4885KDM4E 2739/4885LMNA 3493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.