Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | PTK2B | Q14289 | 1/20 | 1.00 |
| ▸ | ESR2 | Q92731 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 5/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | USP2 | O75604 | 1/20 | 0.70 |
| ▸ | CDK4 | P11802 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
| ▸ | CCND1 | P24385 | 1/20 | 0.70 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.57 |
| ▸ | HRH1 | P35367 | 4/20 | 0.57 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.57 |
| ▸ | HTR1A | P08908 | 3/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.57 |
| ▸ | DRD1 | P21728 | 3/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28863147 | 0.90 | MAPT (0.82) | ALDH1A1MAPTLMNAKDM4EPTK2B | |
| SCHEMBL1450332 | 0.90 | ALDH1A1 (0.82) | ALDH1A1MAPTLMNAKDM4EPTK2B | |
| SCHEMBL30739439 | 0.89 | ALDH1A1 (0.79) | ALDH1A1MAPTLMNAKDM4EPTK2B | |
| SCHEMBL7940135 | 0.83 | ALDH1A1 (1.00) | ALDH1A1MAPTLMNAKDM4EPTK2B | |
| SCHEMBL27493589 | 0.82 | ALDH1A1 (0.70) | ALDH1A1MAPTLMNAKDM4EPTK2B | |
| SCHEMBL4935582 | 0.80 | ALDH1A1 (0.78) | ALDH1A1MAPTLMNAKDM4EPTK2B | |
| SCHEMBL25818505 | 0.79 | ALDH1A1 (0.65) | ALDH1A1MAPTLMNAKDM4EPTK2B | |
| Ammonia Solution, Strong SCHEMBL11729771 | 0.79 | ALDH1A1 (0.75) | ALDH1A1MAPTLMNAKDM4EPTK2B | |
| SCHEMBL30298406 | 0.79 | MAPT (0.64) | ALDH1A1MAPTLMNAKDM4EPTK2B | |
| SCHEMBL10993180 | 0.79 | ALDH1A1 (0.64) | ALDH1A1MAPTLMNAKDM4EPTK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218336-A2 | MELANIN CONCENTRATING HORMONE ANTAGONIST | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001021577-A2 | MELANIN CONCENTRATING HORMONE ANTAGONIST | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-03-29 | — | — | WO | disclosed |