SCHEMBL25818841

SCHEMBL25818841

CCCCCCCCCCCCCC(=O)OC[C@H](COCCOCCOC[C@@H](COC(=O)CCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC

nearest known ligand 0.84

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.84
LMNA P02545 1/20 0.84
PRKCA P17252 4/20 0.72
PRKCE Q02156 2/20 0.72
PRKCQ Q04759 2/20 0.72
PRKCD Q05655 2/20 0.72
LPAR3 Q9UBY5 7/20 0.68
LPAR1 Q92633 4/20 0.68
ENPP2 Q13822 3/20 0.68
SMN1; SMN2 Q16637 1/20 0.68
LPAR2 Q9HBW0 2/20 0.66
FABP3 P05413 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25818802 1.00 ALDH1A1 (0.84) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL1080161 0.98 ALDH1A1 (0.87) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL29306783 0.97 ALDH1A1 (0.79) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL25906604 0.97 ALDH1A1 (0.79) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL26021857 0.97 ALDH1A1 (0.79) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL25449045 0.97 ALDH1A1 (0.79) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL19821333 0.97 ALDH1A1 (0.79) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL18159452 0.94 ALDH1A1 (0.75) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL17448439 0.94 ALDH1A1 (0.75) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL18159456 0.94 ALDH1A1 (0.75) ALDH1A1LMNAPRKCAPRKCEPRKCQ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226219-A1 PEG LIPIDOID COMPOUNDS TRANSLATE BIO, INC. 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226219-A1 PEG LIPIDOID COMPOUNDS LIPG, ABCB4, HDLBP ALDH1A1 3688/4885LMNA 1547/4885PRKCA 1796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.