Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30339049 | 0.92 | GPR119 (0.44) | GPR119RIPK1 | |
| SCHEMBL30338592 | 0.92 | GPR119 (0.44) | GPR119RIPK1 | |
| SCHEMBL25816607 | 0.92 | GPR119 (0.44) | GPR119RIPK1 | |
| SCHEMBL25816609 | 0.92 | GPR119 (0.44) | GPR119RIPK1 | |
| SCHEMBL30547533 | 0.92 | GPR119 (0.44) | GPR119RIPK1 | |
| SCHEMBL25303343 | 0.88 | GPR119 (0.49) | GPR119RIPK1RECQL | |
| SCHEMBL30338800 | 0.88 | GPR119 (0.49) | GPR119RIPK1RECQL | |
| SCHEMBL30547538 | 0.87 | GPR119 (0.44) | GPR119RIPK1 | |
| SCHEMBL30339751 | 0.87 | GPR119 (0.44) | GPR119RIPK1 | |
| SCHEMBL29966726 | 0.87 | GPR119 (0.44) | GPR119RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219937-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | SANOFI (FR) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219937-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | RIPK1, RIPK4, RIPK2 | GPR119 420/4885RIPK1 1/4885RECQL 3201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.