Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 9/20 | 0.58 |
| ▸ | APP | P05067 | 5/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 4/20 | 0.46 |
| ▸ | ACHE | P22303 | 4/20 | 0.46 |
| ▸ | GRK6 | P43250 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25818886 | 0.90 | NTRK1 (0.58) | NTRK1APPRAD52KDM4EALDH1A1 | |
| SCHEMBL25818907 | 0.87 | NTRK1 (0.60) | NTRK1APPRAD52KDM4EALDH1A1 | |
| SCHEMBL20352461 | 0.77 | LMNA (0.40) | ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL2583542 | 0.76 | RAD52 (0.82) | NTRK1APPRAD52KDM4EALDH1A1 | |
| SCHEMBL25818902 | 0.74 | NTRK1 (1.00) | NTRK1GRK6 | |
| SCHEMBL12176297 | 0.69 | SLC2A1 (0.72) | APPRAD52KDM4EALDH1A1LMNA | |
| SCHEMBL22054938 | 0.69 | WHR1 (0.46) | APPLMNAMAPTKMT2ANPSR1 | |
| SCHEMBL12175837 | 0.68 | RAD52 (1.00) | APPRAD52KDM4EALDH1A1LMNA | |
| SCHEMBL16280679 | 0.67 | ACHE (0.80) | APPRAD52KDM4EALDH1A1LMNA | |
| SCHEMBL2590855 | 0.66 | RAD52 (0.82) | NTRK1APPRAD52KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023123883-A1 | METHOD FOR PREPARING QUINAZOLINE DERIVATIVE AND ANALOG THEREOF AND USE THEREOF | 沈阳药科大学 | 2023-07-06 | — | — | WO | disclosed |