Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 11/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25301990 | 0.89 | TLR7 (0.45) | TLR7TLR8CNR2CNR1 | |
| SCHEMBL25819220 | 0.82 | GLS (0.37) | — | |
| SCHEMBL25301816 | 0.81 | TLR7 (0.48) | TLR7TLR8CNR2BRD4 | |
| SCHEMBL31270883 | 0.79 | TLR7 (0.46) | TLR7TLR8CNR2BRD4 | |
| SCHEMBL25255323 | 0.79 | TLR7 (0.46) | TLR7TLR8CNR2BRD4 | |
| SCHEMBL25818897 | 0.78 | TLR7 (0.45) | TLR7TLR8CNR2CNR1BRD4 | |
| SCHEMBL25301552 | 0.73 | RORC (0.37) | CNR2 | |
| SCHEMBL25255294 | 0.73 | TLR7 (0.47) | TLR7TLR8CNR2 | |
| SCHEMBL30484321 | 0.73 | TLR7 (0.48) | TLR7TLR8CNR2BRD4 | |
| SCHEMBL25300018 | 0.73 | TLR7 (0.48) | TLR7TLR8CNR2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125121-A1 | TRICYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |