SCHEMBL25819220 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	GLS	O94925	2/20	0.37

▸	RORC	P51449	2/20	0.36

▸	PDE4D	Q08499	2/20	0.34

▸	PDE4A	P27815	1/20	0.34

▸	PDE4B	Q07343	1/20	0.34

▸	PDE4C	Q08493	1/20	0.34

▸	GPR119	Q8TDV5	8/20	0.34

▸	KDM4E	B2RXH2	1/20	0.34

▸	MAPT	P10636	1/20	0.34

▸	FAAH	O00519	1/20	0.33

▸	FPR2	P25090	1/20	0.33

▸	IDO1	P14902	1/20	0.33

▸	TDO2	P48775	1/20	0.33

▸	CHEK2	O96017	1/20	0.33

▸	TGFBR1	P36897	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25301552	0.92	RORC (0.37)	GLSRORCGPR119KDM4EMAPT
SCHEMBL25819010	0.92	GLS (0.38)	GLSRORCPDE4DPDE4APDE4B
SCHEMBL25819006	0.85	GLS (0.39)	GLSRORCGPR119FAAHFPR2
SCHEMBL31270623	0.85	GLS (0.39)	GLSRORCGPR119FAAHFPR2
SCHEMBL30484348	0.83	RORC (0.37)	GLSRORCGPR119KDM4EMAPT
SCHEMBL25260616	0.83	RORC (0.37)	GLSRORCGPR119KDM4EMAPT
SCHEMBL25819166	0.82	TLR7 (0.45)	—
SCHEMBL25296505	0.79	GLS (0.38)	GLSRORCKDM4EMAPTFPR2
SCHEMBL25262168	0.78	ADORA2B (0.41)	GLSRORCGPR119FAAHCHEK2
SCHEMBL31270748	0.78	ADORA2B (0.41)	GLSRORCGPR119FAAHCHEK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023125121-A1	TRICYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF	四川科伦博泰生物医药股份有限公司	2023-07-06	—	—	WO	disclosed