Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25819187 | 0.87 | LMNA (0.35) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL25956024 | 0.74 | NQO1 (0.56) | MAPTMEN1KMT2ATP53HPGD | |
| SCHEMBL8962018 | 0.74 | NQO1 (0.56) | MAPTMEN1KMT2ATP53HPGD | |
| SCHEMBL3035998 | 0.73 | NQO1 (0.67) | MAPTMEN1KMT2ATP53HPGD | |
| SCHEMBL13382488 | 0.72 | LTA4H (0.46) | MAPTMEN1KMT2ATP53HPGD | |
| SCHEMBL12128744 | 0.70 | SMN1; SMN2 (0.64) | MEN1KMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL22754540 | 0.69 | MEN1 (0.49) | MAPTMEN1KMT2ATP53HPGD | |
| SCHEMBL13209791 | 0.69 | NQO1 (0.58) | MAPTMEN1KMT2ATP53HPGD | |
| SCHEMBL14280093 | 0.69 | SMN1; SMN2 (0.66) | MAPTMEN1KMT2ATP53HPGD | |
| SCHEMBL15541243 | 0.68 | KDM4E (0.43) | MAPTTSHRALDH1A1SMN1; SMN2TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230220158-A1 | IONOMERS WITH MACROCYCLIC MOIETIES FOR ION CONDUCTIVITY AND PERMSELECTIVITY | NATIONAL SCIENCE FOUNDATION | 2023-07-13 | — | — | US | disclosed |