Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 2/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | PTPRB | P23467 | 2/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25819182 | 0.87 | MAPT (0.37) | ALDH1A1SMN1; SMN2HPGDMAPTKDM4E | |
| SCHEMBL25819304 | 0.73 | GAA (0.33) | LMNAALDH1A1PKMSMN1; SMN2HPGD | |
| SCHEMBL8958221 | 0.70 | ING2 (0.59) | ALDH1A1SMN1; SMN2MAPTKDM4EGAA | |
| SCHEMBL25819326 | 0.65 | ING2 (0.42) | ALDH1A1PTPRCPTPN2PTPN1PTPRB | |
| SCHEMBL8962018 | 0.64 | NQO1 (0.56) | ALDH1A1SMN1; SMN2HPGDMAPTKDM4E | |
| SCHEMBL25956024 | 0.64 | NQO1 (0.56) | ALDH1A1SMN1; SMN2HPGDMAPTKDM4E | |
| SCHEMBL3035998 | 0.64 | NQO1 (0.67) | ALDH1A1SMN1; SMN2HPGDMAPTMEN1 | |
| SCHEMBL18863517 | 0.64 | ING2 (0.50) | SMN1; SMN2PTPRCPTPN2PTPN1PTPRB | |
| SCHEMBL13382488 | 0.63 | LTA4H (0.46) | LMNAALDH1A1SMN1; SMN2HPGDMAPT | |
| SCHEMBL755720 | 0.63 | CA12 (0.66) | LMNAALDH1A1PKMSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230220158-A1 | IONOMERS WITH MACROCYCLIC MOIETIES FOR ION CONDUCTIVITY AND PERMSELECTIVITY | NATIONAL SCIENCE FOUNDATION | 2023-07-13 | — | — | US | disclosed |