SCHEMBL25819200

SCHEMBL25819200

CCCOc1c2cc(C)cc1Cc1cc(S(=O)(=O)O)cc(c1O)Cc1cc(-c3ccc(-c4ccc(C)cc4)cc3)cc(c1OCCC)Cc1cccc(c1O)C2

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GSTA1 P08263 6/20 0.51
GSTP1 P09211 6/20 0.51
PTPRC P08575 4/20 0.48
PTPN2 P17706 4/20 0.48
PTPN1 P18031 4/20 0.48
PTPRB P23467 4/20 0.48
PTPN11 Q06124 4/20 0.48
ING2 Q9H160 3/20 0.42
TLR4 O00206 1/20 0.32
CD14 P08571 1/20 0.32
LY96 Q9Y6Y9 1/20 0.32
ERN1 O75460 1/20 0.31
FFAR4 Q5NUL3 1/20 0.30
DUSP5 Q16690 1/20 0.30
DUSP6 Q16828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25819329 0.91 GSTA1 (0.53) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL25819205 0.89 GSTA1 (0.55) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL25819270 0.85 CD69 (0.49) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL18538312 0.82 ING2 (0.62) ING2DUSP5DUSP6
SCHEMBL19726834 0.79 GSTA1 (0.64) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL12856718 0.79 GSTA1 (0.64) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL19762894 0.79 ING2 (0.68) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL18538277 0.78 ING2 (0.45) GSTA1GSTP1PTPN2PTPN1ING2
SCHEMBL18863517 0.78 ING2 (0.50) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL18538311 0.77 ING2 (0.54) ING2DUSP5DUSP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230220158-A1 IONOMERS WITH MACROCYCLIC MOIETIES FOR ION CONDUCTIVITY AND PERMSELECTIVITY NATIONAL SCIENCE FOUNDATION 2023-07-13 US disclosed