SCHEMBL25819205

SCHEMBL25819205

CCCOc1c2cc(C)cc1Cc1cccc(c1O)Cc1cc(-c3ccc(-c4ccc(C)cc4)cc3)cc(c1OCCC)Cc1cccc(c1O)C2

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GSTA1 P08263 6/20 0.55
GSTP1 P09211 6/20 0.55
PTPRC P08575 4/20 0.52
PTPN2 P17706 4/20 0.52
PTPN1 P18031 4/20 0.52
PTPRB P23467 4/20 0.52
PTPN11 Q06124 4/20 0.52
TLR4 O00206 2/20 0.38
CD14 P08571 2/20 0.38
LY96 Q9Y6Y9 2/20 0.38
ERN1 O75460 2/20 0.34
FFAR4 Q5NUL3 1/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
CD69 Q07108 1/20 0.33
CREB1 P16220 1/20 0.32
LTB4R Q15722 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25819200 0.89 GSTA1 (0.51) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL12856718 0.85 GSTA1 (0.64) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL19726834 0.85 GSTA1 (0.64) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL25819333 0.82 GSTA1 (0.50) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL13987036 0.82 GSTA1 (0.52) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL12856732 0.81 GSTA1 (0.67) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL23931194 0.79 GSTA1 (0.58) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL25819329 0.78 GSTA1 (0.53) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL13987037 0.78 TLR4 (0.49) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL760971 0.73 GSTA1 (0.65) GSTA1GSTP1PTPRCPTPN2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230220158-A1 IONOMERS WITH MACROCYCLIC MOIETIES FOR ION CONDUCTIVITY AND PERMSELECTIVITY NATIONAL SCIENCE FOUNDATION 2023-07-13 US disclosed