SCHEMBL25819329

SCHEMBL25819329

CCCOc1c2cc(-c3ccc(-c4ccccc4)cc3)cc1Cc1cc(S(=O)(=O)O)cc(c1O)Cc1cc(-c3ccc(-c4ccccc4)cc3)cc(c1OCCC)Cc1cccc(c1O)C2

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GSTA1 P08263 6/20 0.53
GSTP1 P09211 6/20 0.53
PTPRC P08575 4/20 0.51
PTPN2 P17706 4/20 0.51
PTPN1 P18031 4/20 0.51
PTPRB P23467 4/20 0.51
PTPN11 Q06124 4/20 0.51
ING2 Q9H160 3/20 0.45
CREB1 P16220 1/20 0.37
CD69 Q07108 1/20 0.33
TLR4 O00206 1/20 0.33
CD14 P08571 1/20 0.33
LY96 Q9Y6Y9 1/20 0.33
KAT6A Q92794 1/20 0.33
ERN1 O75460 1/20 0.33
ALDH1A1 P00352 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25819200 0.91 GSTA1 (0.51) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL25819263 0.84 CD69 (0.54) GSTA1GSTP1PTPN2PTPN1ING2
SCHEMBL25819333 0.81 GSTA1 (0.50) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL18863517 0.80 ING2 (0.50) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL18538277 0.79 ING2 (0.45) GSTA1GSTP1PTPN2PTPN1ING2
SCHEMBL25819205 0.78 GSTA1 (0.55) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL25819270 0.78 CD69 (0.49) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL18538306 0.76 ING2 (0.60) PTPN2PTPN1PTPN11ING2ALDH1A1
SCHEMBL18538304 0.76 ING2 (0.60) PTPN2PTPN1PTPN11ING2ALDH1A1
SCHEMBL12856732 0.74 GSTA1 (0.67) GSTA1GSTP1PTPRCPTPN2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230220158-A1 IONOMERS WITH MACROCYCLIC MOIETIES FOR ION CONDUCTIVITY AND PERMSELECTIVITY NATIONAL SCIENCE FOUNDATION 2023-07-13 US disclosed