Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | HTR1B | P28222 | 2/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25822130 | 0.87 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL4568908 | 0.87 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL25826749 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL2210842 | 0.84 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL29818755 | 0.84 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL19291799 | 0.82 | HTR1B (0.51) | SMN1; SMN2ALDH1A1HTR1BHTR1DKDM4E | |
| SCHEMBL25825926 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL12819942 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL12819830 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL12819385 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | SMN1; SMN2 39/4885ALDH1A1 133/4885TP53 4120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.