Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.36 |
| ▸ | GLS | O94925 | 2/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31270874 | 1.00 | KIT (0.36) | KITGLSJAK1MEN1KMT2A | |
| SCHEMBL25254391 | 0.90 | TLR7 (0.34) | CYP3A4 | |
| SCHEMBL31025946 | 0.90 | KIT (0.39) | KITJAK1GPR119 | |
| SCHEMBL25257828 | 0.90 | KIT (0.39) | KITJAK1GPR119 | |
| SCHEMBL31270679 | 0.90 | KIT (0.37) | KITJAK1LMNATP53MAPT | |
| SCHEMBL25301919 | 0.90 | KIT (0.37) | KITJAK1LMNATP53MAPT | |
| SCHEMBL25256681 | 0.89 | GPR119 (0.34) | KITGLSRORCGPR119 | |
| SCHEMBL31270806 | 0.89 | GPR119 (0.34) | KITGLSRORCGPR119 | |
| SCHEMBL31270695 | 0.89 | KIT (0.38) | KITTDP1GPR119LMNATP53 | |
| SCHEMBL25819488 | 0.88 | KDM4E (0.36) | KITTDP1RORCLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125121-A1 | TRICYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |