Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 2/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 5/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 7/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31270874 | 0.88 | KIT (0.36) | KITTP53LMNARORCTDP1 | |
| SCHEMBL25819223 | 0.88 | KIT (0.36) | KITTP53LMNARORCTDP1 | |
| SCHEMBL31270695 | 0.88 | KIT (0.38) | KDM4EPKMKITP2RX3TP53 | |
| SCHEMBL31025946 | 0.84 | KIT (0.39) | KITTLR7 | |
| SCHEMBL25257828 | 0.84 | KIT (0.39) | KITTLR7 | |
| SCHEMBL31270806 | 0.84 | GPR119 (0.34) | KITTLR7RORCNOD2NOD1 | |
| SCHEMBL25256681 | 0.84 | GPR119 (0.34) | KITTLR7RORCNOD2NOD1 | |
| SCHEMBL25301919 | 0.83 | KIT (0.37) | KITTP53TLR7LMNATHRB | |
| SCHEMBL31270679 | 0.83 | KIT (0.37) | KITTP53TLR7LMNATHRB | |
| SCHEMBL29263585 | 0.82 | TLR7 (0.33) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125121-A1 | TRICYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |