Sugi Predict

Sugi Predict / Compounds / SCHEMBL31270695

SCHEMBL31270695

SCHEMBL31270695

CCCCc1nc2c(NC(C)(C)C)nc3cc(C4=CCN(C(=O)OCc5ccccc5)CC4)sc3c2n1CC1CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KIT P10721 2/20 0.38
▸ HTT P42858 1/20 0.35
▸ CYP2D6 P10635 1/20 0.35
▸ CYP2C9 P11712 1/20 0.35
▸ GRIN2B Q13224 1/20 0.35
▸ LMNA P02545 4/20 0.35
▸ THRB P10828 2/20 0.35
▸ P2RX3 P56373 1/20 0.35
▸ GPR119 Q8TDV5 1/20 0.34
▸ TLR7 Q9NYK1 2/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ TP53 P04637 3/20 0.34
▸ MAPT P10636 2/20 0.34
▸ YAP1 P46937 1/20 0.34
▸ NPC1 O15118 1/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ PRMT1 Q99873 1/20 0.34
▸ KDM4E B2RXH2 1/20 0.33
▸ PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25819223 0.89 KIT (0.36) KITLMNAGPR119TDP1TP53
SCHEMBL31270874 0.89 KIT (0.36) KITLMNAGPR119TDP1TP53
SCHEMBL25819488 0.88 KDM4E (0.36) KITLMNATHRBP2RX3TLR7
SCHEMBL31025946 0.87 KIT (0.39) KITGPR119TLR7
SCHEMBL25257828 0.87 KIT (0.39) KITGPR119TLR7
SCHEMBL31270679 0.86 KIT (0.37) KITLMNATHRBTLR7TP53
SCHEMBL25301919 0.86 KIT (0.37) KITLMNATHRBTLR7TP53
SCHEMBL25256681 0.84 GPR119 (0.34) KITGPR119TLR7
SCHEMBL31270806 0.84 GPR119 (0.34) KITGPR119TLR7
SCHEMBL29263585 0.82 TLR7 (0.33) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260055119-A9 TRICYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF SICHUAN KELUN BIOTECH BIOPHARMACEUTICAL CO LTD (CN) 2026-02-26 — — US disclosed
US-20250257071-A9 TRICYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2025-08-14 — — US disclosed
US-20250002502-A1 TRICYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF SICHUAN KELUN BIOTECH BIOPHARMACEUTICAL CO LTD (CN) 2025-01-02 — — US disclosed
EP-4458830-A1 TRICYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) 2024-11-06 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250257071-A9 TRICYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF CYP11B2, CYP11B1, CYP3A5 KIT 1622/4885HTT 1497/4885CYP2D6 13/4885
US-20260055119-A9 TRICYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF CYP11B1, CYP11B2, CYP2D6 KIT 3679/4885HTT 4000/4885CYP2D6 3/4885
US-20250002502-A1 TRICYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF CYP11B2, CYP11B1, CYP3A5 KIT 1622/4885HTT 1497/4885CYP2D6 13/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.