Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | TLR4 | O00206 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13881591 | 0.87 | KDM4E (0.40) | KDM4EMEN1KMT2APARP15PARP10 | |
| SCHEMBL25822137 | 0.87 | PARP10 (0.40) | KDM4EMEN1KMT2APARP15PARP10 | |
| SCHEMBL19291642 | 0.86 | HTR1B (0.50) | KDM4ECARM1PRMT6HTR1DHTR1B | |
| SCHEMBL18721737 | 0.86 | HTR1B (0.50) | KDM4ECARM1PRMT6HTR1DHTR1B | |
| SCHEMBL25819210 | 0.86 | HTR1B (0.50) | KDM4ECARM1PRMT6HTR1DHTR1B | |
| SCHEMBL19291799 | 0.84 | HTR1B (0.51) | KDM4ECARM1PRMT6HTR1DHTR1B | |
| SCHEMBL4568903 | 0.84 | CYP1A2 (0.41) | PARP15PARP10MAOAMAOBTLR4 | |
| SCHEMBL29818658 | 0.82 | PARP10 (0.43) | PARP15PARP10 | |
| SCHEMBL2204706 | 0.82 | PARP10 (0.43) | PARP15PARP10 | |
| SCHEMBL25822091 | 0.81 | HTR1B (0.51) | KDM4ECARM1PRMT6HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | KDM4E 2227/4885CARM1 3318/4885PRMT6 3578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.