Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29862066 | 0.76 | ALOX5 (0.33) | AKT1ESR1ESR2 | |
| SCHEMBL34461266 | 0.74 | AKT1 (0.37) | AKT1ESR1ESR2 | |
| SCHEMBL30959512 | 0.70 | — | — | |
| SCHEMBL31461881 | 0.70 | PTGS2 (0.40) | AKT1 | |
| SCHEMBL24755126 | 0.68 | CYP3A4 (0.38) | AKT1ESR1ESR2 | |
| SCHEMBL31650060 | 0.66 | KDM1A (0.39) | — | |
| SCHEMBL31283953 | 0.64 | ALOX5 (0.53) | — | |
| SCHEMBL29383596 | 0.63 | MAOA (0.37) | AKT1 | |
| SCHEMBL3002812 | 0.63 | BCL2L1 (0.38) | AKT1ESR1ESR2 | |
| SCHEMBL22618607 | 0.63 | MAOA (0.37) | AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125989-A1 | QUINAZOLINE COMPOUND AND APPLICATION THEREOF | 上海医药集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |