Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23248918 | 0.91 | OPRK1 (0.33) | POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL23256173 | 0.90 | OPRK1 (0.35) | MEN1KMT2AALDH1A1SMN1; SMN2AVPR1B | |
| SCHEMBL23250150 | 0.85 | OPRK1 (0.32) | POLBALDH1A1AVPR1B | |
| SCHEMBL23256342 | 0.84 | TERT (0.31) | POLBMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL29863481 | 0.84 | OPRK1 (0.32) | ALDH1A1 | |
| SCHEMBL23255954 | 0.83 | OPRK1 (0.31) | POLBALDH1A1 | |
| SCHEMBL24555664 | 0.82 | LNPEP (0.32) | MEN1KMT2AALDH1A1SMN1; SMN2AVPR1B | |
| SCHEMBL31629365 | 0.82 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL23256585 | 0.82 | MEN1 (0.33) | POLBMEN1KMT2ASMN1; SMN2CNR2 | |
| SCHEMBL23256514 | 0.82 | EPHX2 (0.33) | POLBSMN1; SMN2AVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125182-A1 | PROPIONIC ACID DERIVATIVE AND MEDICAL USE THEREOF | 海思科医药集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |