Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | TLR4 | O00206 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4568865 | 0.86 | TLR4 (0.44) | HTR2CSLC6A4SLC2A1TLR4TLR2 | |
| SCHEMBL25819210 | 0.84 | HTR1B (0.50) | CARM1PRMT6TLR4TLR2SIRT2 | |
| SCHEMBL19291642 | 0.84 | HTR1B (0.50) | CARM1PRMT6TLR4TLR2SIRT2 | |
| SCHEMBL18721737 | 0.84 | HTR1B (0.50) | CARM1PRMT6TLR4TLR2SIRT2 | |
| SCHEMBL2205862 | 0.84 | TLR4 (0.44) | SLC2A1TLR4TLR2SIRT2KAT6A | |
| SCHEMBL29818750 | 0.84 | TLR4 (0.44) | SLC2A1TLR4TLR2SIRT2KAT6A | |
| SCHEMBL19291799 | 0.83 | HTR1B (0.51) | CARM1PRMT6TLR4TLR2SIRT2 | |
| SCHEMBL19291800 | 0.82 | CHRM2 (0.47) | HTR2CSLC6A4CARM1PRMT6SLC2A1 | |
| SCHEMBL25819673 | 0.82 | CHRM2 (0.47) | HTR2CSLC6A4CARM1PRMT6SLC2A1 | |
| SCHEMBL2204692 | 0.82 | CHRM2 (0.47) | HTR2CSLC6A4CARM1PRMT6SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | HTR2C 2110/4885SLC6A4 1527/4885CARM1 3318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.