Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.67 |
| ▸ | MAPT | P10636 | 9/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.61 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.60 |
| ▸ | DHODH | Q02127 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2581990 | 1.00 | ALDH1A1 (0.67) | ALDH1A1MAPTKDM4ETP53PDCD1 | |
| SCHEMBL988238 | 0.91 | MAPT (0.71) | ALDH1A1MAPTKDM4ETP53PDCD1 | |
| SCHEMBL278655 | 0.91 | MAPT (0.71) | ALDH1A1MAPTKDM4ETP53PDCD1 | |
| SCHEMBL988236 | 0.91 | MAPT (0.71) | ALDH1A1MAPTKDM4ETP53PDCD1 | |
| SCHEMBL4317761 | 0.90 | ALDH1A1 (0.81) | ALDH1A1MAPTKDM4EPDCD1CD274 | |
| SCHEMBL2139678 | 0.90 | ALDH1A1 (0.81) | ALDH1A1MAPTKDM4EPDCD1CD274 | |
| SCHEMBL2139676 | 0.90 | ALDH1A1 (0.81) | ALDH1A1MAPTKDM4EPDCD1CD274 | |
| SCHEMBL15392279 | 0.88 | MAPT (0.71) | ALDH1A1MAPTKDM4ETP53PDCD1 | |
| SCHEMBL16131599 | 0.86 | ALDH1A1 (0.64) | ALDH1A1MAPTKDM4ETP53PDCD1 | |
| SCHEMBL15371833 | 0.86 | ALDH1A1 (0.64) | ALDH1A1MAPTKDM4ETP53PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3483194-A1 | METHOD FOR PREPARING POLYURETHANE RESIN AND POLYURETHANE RESIN PREPARED THEREBY | Covestro Deutschland AG (DE) | 2019-05-15 | — | — | EP | disclosed |
| EP-2585033-A2 | COSMETIC AND TOPICAL SKIN PREPARATION COMPRISING HIGHER ALCOHOL-MODIFIED SILICONE | Dow Corning Toray Co., Ltd. (JP) | 2013-05-01 | — | — | EP | disclosed |
| WO-2011136389-A2 | COSMETIC AND TOPICAL SKIN PREPARATION COMPRISING HIGHER ALCOHOL-MODIFIED SILICONE | DOW CORNING TORAY CO., LTD. (JP) | 2011-11-03 | — | — | WO | disclosed |