Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.71 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.71 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | POLB | P06746 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.66 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CASP3 | P42574 | 1/20 | 0.62 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.62 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL988238 | 1.00 | MAPT (0.71) | MAPTPDCD1CD274ALDH1A1KDM4E | |
| SCHEMBL278655 | 1.00 | MAPT (0.71) | MAPTPDCD1CD274ALDH1A1KDM4E | |
| SCHEMBL2139678 | 0.92 | ALDH1A1 (0.81) | MAPTPDCD1CD274ALDH1A1KDM4E | |
| SCHEMBL4317761 | 0.92 | ALDH1A1 (0.81) | MAPTPDCD1CD274ALDH1A1KDM4E | |
| SCHEMBL2139676 | 0.92 | ALDH1A1 (0.81) | MAPTPDCD1CD274ALDH1A1KDM4E | |
| SCHEMBL2581990 | 0.91 | ALDH1A1 (0.67) | MAPTPDCD1CD274ALDH1A1KDM4E | |
| SCHEMBL2581988 | 0.91 | ALDH1A1 (0.67) | MAPTPDCD1CD274ALDH1A1KDM4E | |
| SCHEMBL10719867 | 0.89 | MAPT (0.82) | MAPTPDCD1CD274ALDH1A1KDM4E | |
| SCHEMBL10719869 | 0.89 | MAPT (0.82) | MAPTPDCD1CD274ALDH1A1KDM4E | |
| SCHEMBL16131599 | 0.89 | ALDH1A1 (0.64) | MAPTPDCD1CD274ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076133-A | Composite material, composition, preparation method of composite material, light-emitting device and display device | TCL科技集团股份有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-117645581-A | Method for synthesizing series of functional groups of photocatalytic inert C (sp 3) -H bond | 浙江工业大学台州研究院 | 2024-03-05 | — | — | CN | claimed |
| US-20060085922-A1 | Oxidizing composition comprising at least one electrophilic monomer and at least one non-benzoquinone oxidant | L'OREAL S.A. (FR) | 2006-04-27 | — | — | US | claimed |
| EP-3883577-B1 | COMPOSITIONS AND METHODS OF MODULATING SHORT-CHAIN DEHYDROGENASE ACTIVITY | UNIV CASE WESTERN RESERVE (US) | 2026-04-08 | — | — | EP | disclosed |
| US-12336982-B2 | Compositions and methods of modulating short-chain dehydrogenase activity | RODEO THERAPEUTICS CORPORATION (US) | 2025-06-24 | — | — | US | disclosed |
| CN-120136926-A | Catalyst for condensation reaction of aldehyde and ethyl cyanoacetate Knoevenagel and preparation method thereof | 河北松辰医药科技有限公司 | 2025-06-13 | — | — | CN | disclosed |
| US-20250161277-A1 | COMPOSITIONS AND METHODS OF MODULATING SHORT-CHAIN DEHYDROGENASE ACTIVITY | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2025-05-22 | — | — | US | disclosed |
| CN-118076133-A | Composite material, composition, preparation method of composite material, light-emitting device and display device | TCL科技集团股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-117645581-A | Method for synthesizing series of functional groups of photocatalytic inert C (sp 3) -H bond | 浙江工业大学台州研究院 | 2024-03-05 | — | — | CN | disclosed |
| CN-117299202-A | Quaternary ammonium ion liquid hybridized MCM-41 solid base catalyst and preparation method thereof | 常州大学 | 2023-12-29 | — | — | CN | disclosed |
| WO-2023125498-A1 | ORGANIC COMPOUND, MIXTURE AND COMPOSITION COMPRISING SAME, ORGANIC ELECTRONIC DEVICE, AND APPLICATIONS OF COMPOUND | 浙江光昊光电科技有限公司 | 2023-07-06 | — | — | WO | disclosed |
| US-20060088493-A1 | Composition and process for the cosmetic treatment of keratin materials based on electrophilic monomers and non-silicone polymers | L'OREAL S.A. (FR) | 2006-04-27 | — | — | US | disclosed |
| US-20060085922-A1 | Oxidizing composition comprising at least one electrophilic monomer and at least one non-benzoquinone oxidant | L'OREAL S.A. (FR) | 2006-04-27 | — | — | US | disclosed |
| US-20060083706-A1 | Haircare composition comprising at least one electrophilic monomer and micro- or nanoparticles of at least one solid lubricant | L'OREAL S.A. (FR) | 2006-04-20 | — | — | US | disclosed |
| US-20060083762-A1 | Uses of compositions comprising electrophilic monomers and micro-particles or nanoparticles | L'OREAL S.A. (FR) | 2006-04-20 | — | — | US | disclosed |
| US-20060080792-A1 | Film-forming composition for the cosmetic treatment of keratin materials comprising at least one electrophilic monomer and at least one non-silicone polymer | L'OREAL S.A. (FR) | 2006-04-20 | — | — | US | disclosed |
| US-20060078523-A1 | Composition comprising at least one electrophilic monomer and at least one acid in a cosmetically acceptable anhydrous medium, and use thereof for cosmetic treatment of the hair | L'OREAL S.A. (FR) | 2006-04-13 | — | — | US | disclosed |
| US-20060078522-A1 | Composition for treating keratin materials comprising at least one electrophilic monomer and at least one salt | L'OREAL S.A. (FR) | 2006-04-13 | — | — | US | disclosed |
| WO-2006024611-A2 | STABILIZATION OF ORGANIC MATERIALS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-03-09 | — | — | WO | disclosed |
| US-6645991-B1 | Glycoprotein adhesion receptor antagonists such as 3-phenyl-4-(4-(3-(pyridin-2-ylamino)propoxy)phenyl)-butyric acid, used for prophylaxis of tumors, osteoporosis, cardiovascular diseases, fibrosis, inflammation, infections or psoriasis | MERCK PATENT GMBH (DE) | 2003-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250161277-A1 | COMPOSITIONS AND METHODS OF MODULATING SHORT-CHAIN DEHYDROGENASE ACTIVITY | HPGD, GCDH, HPGDS | MAPT 4066/4885PDCD1 2682/4885CD274 4512/4885 |
| US-20060088493-A1 | Composition and process for the cosmetic treatment of keratin materials based on electrophilic monomers and non-silicone polymers | KRT18, CUTA, MARK1 | MAPT 366/4885PDCD1 2073/4885CD274 1961/4885 |
| US-12336982-B2 | Compositions and methods of modulating short-chain dehydrogenase activity | HPGD, GCDH, HPGDS | MAPT 4066/4885PDCD1 2682/4885CD274 4512/4885 |
| US-20060083762-A1 | Uses of compositions comprising electrophilic monomers and micro-particles or nanoparticles | KRT18, PRKDC, ACP1 | MAPT 355/4885PDCD1 2607/4885CD274 2263/4885 |
| US-20060085922-A1 | Oxidizing composition comprising at least one electrophilic monomer and at least one non-benzoquinone oxidant | KRT18, GPX4, NOX4 | MAPT 2098/4885PDCD1 4576/4885CD274 4667/4885 |
| US-20060083706-A1 | Haircare composition comprising at least one electrophilic monomer and micro- or nanoparticles of at least one solid lubricant | MITF, CUTA, NACA | MAPT 865/4885PDCD1 1137/4885CD274 1096/4885 |
| US-20060078523-A1 | Composition comprising at least one electrophilic monomer and at least one acid in a cosmetically acceptable anhydrous medium, and use thereof for cosmetic treatment of the hair | HOGA1, OAT, SUCLG1 | MAPT 1711/4885PDCD1 1738/4885CD274 2670/4885 |
| US-20060078522-A1 | Composition for treating keratin materials comprising at least one electrophilic monomer and at least one salt | KRT18, DSG1, DSC1 | MAPT 215/4885PDCD1 2957/4885CD274 2524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.