SCHEMBL25819880

SCHEMBL25819880

CC1(C)OC[C@H](Cn2cnc3c(N)ncnc32)O1

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 8/20 0.51
ADORA1 P30542 4/20 0.51
PI4KA P42356 4/20 0.51
PI4K2B Q8TCG2 4/20 0.51
PI4K2A Q9BTU6 4/20 0.51
PI4KB Q9UBF8 4/20 0.51
ADORA2B P29275 1/20 0.49
AHCY P23526 4/20 0.48
METTL3 Q86U44 1/20 0.43
METTL14 Q9HCE5 1/20 0.43
ALDH1A1 P00352 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL987717 0.88 ADORA2A (0.56) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL12898069 0.78 ALDH1A1 (0.36) ADORA2AALDH1A1
SCHEMBL12898082 0.78 ALDH1A1 (0.36) ADORA2AALDH1A1
SCHEMBL4084012 0.78 ADORA2A (0.56) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL23710675 0.75 ALDH1A1 (0.42) ALDH1A1
SCHEMBL8923800 0.73 ADORA2A (0.56) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL6757983 0.72 ADORA2A (0.60) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL10047656 0.72 ADORA2A (0.47) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL12898072 0.72 ALDH1A1 (0.39) ALDH1A1
SCHEMBL12898083 0.72 ALDH1A1 (0.39) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023131170-A1 DOUBLE-STRANDED RNA HAVING NUCLEOTIDE ANALOG 大睿生物医药科技(上海)有限公司 2023-07-13 WO disclosed