Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.56 |
| ▸ | PI4KA | P42356 | 3/20 | 0.51 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.51 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.51 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.51 |
| ▸ | AHCY | P23526 | 8/20 | 0.51 |
| ▸ | ADA | P00813 | 1/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.48 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.48 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.48 |
| ▸ | GAPDH | P04406 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | STAT6 | P42226 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921749 | 0.84 | ADORA1 (0.40) | ADORA2AADORA1AHCYADAMAPK1 | |
| SCHEMBL22352153 | 0.82 | MARS1 (0.46) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL8921016 | 0.82 | ADORA2A (0.52) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL10835714 | 0.81 | ADORA2A (0.58) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL18410857 | 0.81 | MAPK1 (0.57) | ADORA1MAPK1 | |
| SCHEMBL8921694 | 0.81 | CYP1A2 (0.51) | ADORA1MAPK1STAT6SMN1; SMN2SLC29A1 | |
| SCHEMBL23680075 | 0.81 | AHCY (0.49) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL18526553 | 0.81 | ADORA2A (0.49) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL3541 | 0.81 | ADA (0.65) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL10381269 | 0.81 | ADA (0.65) | ADORA2AADORA1PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703224-A | Antiviral c-nucleoside derivatives | NIPPON SHINYAKU CO. LTD. (JP) | 1997-12-30 | — | — | US | disclosed |
| EP-0733630-A1 | NUCLEOSIDE DERIVATIVE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1996-09-25 | — | — | EP | disclosed |