Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25821885 | 0.96 | BCHE (0.53) | BCHETDP1L3MBTL1DRD2DRD4 | |
| SCHEMBL25822292 | 0.88 | DRD4 (0.47) | BCHETDP1L3MBTL1DRD2DRD4 | |
| SCHEMBL25820053 | 0.87 | BCHE (0.52) | BCHETDP1L3MBTL1DRD2DRD4 | |
| SCHEMBL25822267 | 0.87 | DRD4 (0.48) | BCHETDP1L3MBTL1DRD2DRD4 | |
| SCHEMBL2208231 | 0.85 | TDP1 (0.51) | BCHETDP1L3MBTL1MGLLCYP4F2 | |
| SCHEMBL25822248 | 0.84 | DRD4 (0.48) | BCHEDRD2DRD4DRD3MAOB | |
| SCHEMBL2204637 | 0.84 | CYP4F2 (0.50) | BCHETDP1L3MBTL1MGLLCYP4F2 | |
| SCHEMBL25819946 | 0.83 | BCHE (0.53) | BCHETDP1L3MBTL1DRD2DRD4 | |
| SCHEMBL4568889 | 0.83 | TDP1 (0.55) | BCHETDP1L3MBTL1MGLLCYP4F2 | |
| SCHEMBL25821806 | 0.81 | KDM4E (0.56) | BCHEDRD2DRD4DRD3SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | BCHE 1649/4885TDP1 529/4885L3MBTL1 2438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.