Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.47 |
| ▸ | DRD2 | P14416 | 4/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25822267 | 0.99 | DRD4 (0.48) | DRD4DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL25822248 | 0.96 | DRD4 (0.48) | DRD4DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL25822271 | 0.92 | ADRA1D (0.49) | DRD4DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL25820039 | 0.88 | BCHE (0.52) | DRD4DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL25822293 | 0.86 | HTR1B (0.57) | DRD4DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL13881714 | 0.84 | HTR1B (0.58) | DRD4DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL29818742 | 0.84 | TAAR1 (0.53) | TDP1L3MBTL1MAOB | |
| SCHEMBL2207512 | 0.84 | TAAR1 (0.53) | TDP1L3MBTL1MAOB | |
| SCHEMBL25821885 | 0.84 | BCHE (0.53) | DRD4DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL2207600 | 0.82 | TAAR1 (0.55) | TDP1L3MBTL1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | DRD4 1241/4885DRD2 1703/4885ADRA1D 409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.