Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.33 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | GAK | O14976 | 1/20 | 0.32 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.32 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.32 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 2/20 | 0.31 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.31 |
| ▸ | CLK2 | P49760 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | CCNC | P24863 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25821117 | 0.87 | CDK8 (0.38) | TRPV1ROCK2MTNR1AMTNR1BMAP3K14 | |
| SCHEMBL25821116 | 0.85 | MAP3K14 (0.38) | TRPV1ROCK2MAP3K14ACACBGAK | |
| SCHEMBL25821192 | 0.83 | CDK8 (0.45) | GAKRIPK2COQ8ANLKCDK8 | |
| SCHEMBL25820092 | 0.83 | GABRA1 (0.34) | TRPV1ROCK2MTNR1AMTNR1BMAP3K14 | |
| SCHEMBL25820075 | 0.78 | CCNC (0.42) | TRPV1ROCK2GAKCDK8CCNC | |
| SCHEMBL16288743 | 0.76 | SMN1; SMN2 (0.49) | MAP3K14GAKRIPK2COQ8ANLK | |
| SCHEMBL25820095 | 0.76 | HTR1A (0.51) | TRPV1ROCK2MTNR1AMTNR1BLOXL2 | |
| SCHEMBL25820130 | 0.75 | KDM4E (0.43) | TRPV1ROCK2MTNR1AMTNR1BLOXL2 | |
| SCHEMBL16288742 | 0.73 | MAP3K14 (0.34) | MAP3K14GAKRIPK2COQ8ANLK | |
| SCHEMBL25820108 | 0.72 | IP6K1 (0.43) | TRPV1ROCK2GSK3AGSK3BCLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | TRPV1 4682/4885ROCK2 1486/4885MTNR1A 1625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.