SCHEMBL258202

SCHEMBL258202

COc1cc(CC(N)=O)ccc1O

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.73
TSHR P16473 2/20 0.73
ALDH1A1 P00352 1/20 0.73
NFKB1 P19838 1/20 0.73
TDP1 Q9NUW8 1/20 0.73
TAAR1 Q96RJ0 2/20 0.62
MAPK1 P28482 1/20 0.62
LMNA P02545 1/20 0.60
GLA P06280 1/20 0.60
ALOX5 P09917 1/20 0.58
OR51E2 Q9H255 1/20 0.58
KDM1A O60341 1/20 0.57
FOS P01100 1/20 0.56
TTR P02766 1/20 0.56
JUN P05412 1/20 0.56
NR3C1 P04150 1/20 0.56
HSD17B1 P14061 1/20 0.56
HSD17B2 P37059 1/20 0.56
MEN1 O00255 1/20 0.55
MAPT P10636 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1033641 0.87 LMNA (0.61) GAAALDH1A1MAPK1LMNAGLA
SCHEMBL29602721 0.87 LMNA (0.61) GAAALDH1A1MAPK1LMNAGLA
SCHEMBL5724393 0.86 GAA (0.73) GAATSHRALDH1A1NFKB1TDP1
SCHEMBL7114863 0.86 TSHR (0.77) GAATSHRALDH1A1NFKB1TDP1
SCHEMBL19545803 0.85 GAA (0.71) GAATSHRALDH1A1NFKB1TDP1
Homovanillic Acid SCHEMBL8792 0.84 GAA (1.00) GAATSHRALDH1A1NFKB1TDP1
SCHEMBL1682653 0.84 TSHR (0.75) GAATSHRALDH1A1NFKB1TDP1
SCHEMBL30310281 0.84 TSHR (0.75) GAATSHRALDH1A1NFKB1TDP1
SCHEMBL30310280 0.84 TSHR (0.75) GAATSHRALDH1A1NFKB1TDP1
Homovanillic Acid SCHEMBL10535396 0.84 GAA (1.00) GAATSHRALDH1A1NFKB1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8329948-B2 Method for the synthesis of substituted formylamines and substituted amines BOBYLEV MIKHAIL (US) 2012-12-11 US claimed
EP-1517880-B1 PRODUCTION OF CIS-PELLITORIN AND USE AS A FLAVOURING SYMRISE AG (DE) 2011-01-05 EP claimed
EP-2175854-A1 IMPROVED METHOD FOR THE SYNTHESIS OF SUBSTITUTED FORMYLAMINES AND SUBSTITUTED AMINES University Of North Dakota Research Foundation (US) 2010-04-21 EP claimed
US-20090143622-A1 Method For The Synthesis Of Substituted Formylamines And Substituted Amines BOBYLEV MIKHAIL 2009-06-04 US claimed
WO-2009018353-A1 IMPROVED METHOD FOR THE SYNTHESIS OF SUBSTITUTED FORMYLAMINES AND SUBSTITUTED AMINES UNIVERSITY OF NORTH DAKOTA RESEARCH FOUNDATION (US) 2009-02-05 WO claimed
EP-1633348-B1 4- BROMO - 5 - (2- CHLORO - BENZOYLAMINO) - 1H - PYRAZOLE - 3 - CARBOXYLIC ACID AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B sb 1 /sb RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES ELAN PHARM INC (US) 2008-10-08 EP claimed
US-20050020659-A1 Substituted pyrazole derivatives and related compounds as bradykinin B1 receptor antagonists ELAN PHARMACEUTICALS, INC. 2005-01-27 US claimed
US-20030191069-A1 2-oxoquinoline compounds and pharmaceutical uses thereof JAPAN TOBACCO, INC (JP) 2003-10-09 US claimed
US-6509352-B1 Selectively act on cannabinoid receptors, particularly on peripheral type cannabinoid receptors, and have fewer side effects on the central nervous system, having great immunosuppressive action, anti-inflammatory action or JAPAN TOBACCO INC. (JP) 2003-01-21 US claimed
EP-1142877-A1 2-OXOQUINOLINE COMPOUNDS AND MEDICINAL USES THEREOF JAPAN TOBACCO INC. (JP) 2001-10-10 EP claimed
US-12030326-B2 System and method for printing and drying flavors and fragrances INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2024-07-09 US disclosed
US-20240180220-A1 HYDROGEL ENCAPSULATIONS AND METHODS OF MAKING THE SAME INTERNATIONAL FLAVORS & FRANGRANCES INC. 2024-06-06 US disclosed
WO-2024100137-A1 CELL COMPOSITIONS GIVAUDAN SA (CH) 2024-05-16 WO disclosed
US-11950607-B2 Myceliated vegetable protein and food compositions comprising same Mycotechnology, Inc. (US) 2024-04-09 US disclosed
US-11937622-B2 Obtaining a volatile fraction from juices or alcoholic beverages SYMRISE AG (DE) 2024-03-26 US disclosed
EP-0874805-A1 PHENYLACETAMIDE DERIVATIVES Korea Research Institute of Chemical Technology (KR) 1998-11-04 EP disclosed
WO-1997021668-A1 PHENYLACETAMIDE DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1997-06-19 WO disclosed
EP-0089710-B1 NOVEL HYDROXYPHENYLACETAMIDES HAVING ANALGESIC AND ANTI-IRRITANT ACTIVITY THE PROCTER & GAMBLE COMPANY (US) 1985-07-31 EP disclosed
US-4424205-A DEPILLATORIES THE PROCTER & GAMBLE COMPANY (US) 1984-01-03 US disclosed
EP-0089710-A1 Novel hydroxyphenylacetamides having analgesic and anti-irritant activity THE PROCTER & GAMBLE COMPANY (US) 1983-09-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050020659-A1 Substituted pyrazole derivatives and related compounds as bradykinin B1 receptor antagonists BDKRB1, BDKRB2, BRS3 GAA 4207/4885TSHR 898/4885ALDH1A1 3054/4885
US-20030191069-A1 2-oxoquinoline compounds and pharmaceutical uses thereof CNR2, CNR1, OPRL1 GAA 4692/4885TSHR 2580/4885ALDH1A1 2343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.