Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25822499 | 0.82 | ADAM17 (0.31) | IKBKB | |
| SCHEMBL25820240 | 0.81 | CHRM3 (0.33) | IKBKB | |
| SCHEMBL25821273 | 0.79 | IKBKB (0.32) | IKBKB | |
| SCHEMBL25820234 | 0.78 | HTR2A (0.34) | — | |
| SCHEMBL25820238 | 0.76 | NOS3 (0.42) | IKBKBCYP1A2 | |
| SCHEMBL25820213 | 0.76 | HTR2A (0.43) | — | |
| SCHEMBL25821294 | 0.75 | KMT2A (0.33) | — | |
| SCHEMBL25821293 | 0.73 | HTR2A (0.33) | — | |
| SCHEMBL25821292 | 0.73 | TLR9 (0.38) | — | |
| SCHEMBL26311908 | 0.68 | ALDH1A1 (0.43) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | IKBKB 226/4885CYP1A2 3870/4885CHRM4 4638/4885 |
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | IKBKB 223/4885CYP1A2 3528/4885CHRM4 4284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.