Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | CBLB | Q13191 | 2/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24010362 | 0.93 | P2RX3 (0.35) | CBLBP2RX3GRM4MAP3K5 | |
| SCHEMBL25820805 | 0.90 | SCN9A (0.36) | GCKCBLBMAPTALDH1A1GAA | |
| SCHEMBL25820799 | 0.89 | NPC1 (0.38) | GCKCBLBGAAKDRLMNA | |
| SCHEMBL25827154 | 0.86 | SCN9A (0.39) | CBLBMAPK1GRM4NFKB1NR2C2 | |
| SCHEMBL24010356 | 0.86 | MAPK13 (0.38) | CBLBP2RX3GAATSHRKDR | |
| SCHEMBL25820876 | 0.82 | NPC1 (0.38) | GAAKDRLMNAHTTKDM4E | |
| SCHEMBL25821627 | 0.79 | NPC1 (0.41) | CBLBGAAKDRLMNAMAPK1 | |
| SCHEMBL24003929 | 0.78 | CYP11B2 (0.39) | P2RX3KDRNPC1RAB9AMAP3K5 | |
| SCHEMBL23999768 | 0.77 | NPC1 (0.40) | P2RX3MAPTKDM4ENPC1TP53 | |
| SCHEMBL23999779 | 0.77 | P2RX3 (0.36) | P2RX3MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | GCK 1024/4885CBLB 3851/4885P2RX3 2096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.