Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.34 |
| ▸ | CBLB | Q13191 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.33 |
| ▸ | NR2C2 | P49116 | 3/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.33 |
| ▸ | RELA | Q04206 | 3/20 | 0.33 |
| ▸ | TAB1 | Q15750 | 3/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25820805 | 0.96 | SCN9A (0.36) | SCN9AMAPK13ADAM17MAPK1CBLB | |
| SCHEMBL24010362 | 0.93 | P2RX3 (0.35) | SCN9AMAPK13ADAM17CBLBGRM4 | |
| SCHEMBL25820797 | 0.86 | GCK (0.36) | MAPK1CBLBNFKB1NR2C2NFKB2 | |
| SCHEMBL25827086 | 0.85 | CYP11B2 (0.39) | SCN9AMAPK13ADAM17MAPK1CBLB | |
| SCHEMBL25488380 | 0.83 | CYP11B2 (0.32) | SCN9AMAPK1SCN5A | |
| SCHEMBL25820789 | 0.82 | NPC1 (0.41) | ADAM17MAPK1CBLBNFKB1NFKB2 | |
| SCHEMBL24010356 | 0.81 | MAPK13 (0.38) | MAPK13ADAM17MAPK1CBLBGRM4 | |
| SCHEMBL25820799 | 0.74 | NPC1 (0.38) | CBLBNFKB1NFKB2RELA | |
| SCHEMBL24003929 | 0.73 | CYP11B2 (0.39) | MAPK13CHEK1PDPK1MAP4K4EGFR | |
| SCHEMBL24003861 | 0.72 | CYP11B2 (0.38) | MAPK1CBLBAPPMAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | SCN9A 4086/4885MAPK13 84/4885ADAM17 4191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.