Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.54 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.53 |
| ▸ | ENPEP | Q07075 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dihydrolipoic Acid SCHEMBL4761911 | 0.98 | FOLH1 (0.52) | FOLH1GSTK1ENPEPLMNAANPEP | |
| Dihydrolipoic Acid SCHEMBL618576 | 0.98 | FOLH1 (0.56) | FOLH1GSTK1ENPEPLMNAANPEP | |
| Dihydrolipoic Acid SCHEMBL19773 | 0.98 | FOLH1 (0.56) | FOLH1GSTK1ENPEPLMNAANPEP | |
| Dihydrolipoic Acid SCHEMBL867951 | 0.98 | FOLH1 (0.56) | FOLH1GSTK1ENPEPLMNAANPEP | |
| Dihydrolipoic Acid SCHEMBL1115003 | 0.98 | FOLH1 (0.56) | FOLH1GSTK1ENPEPLMNAANPEP | |
| Dihydrolipoic Acid SCHEMBL2578740 | 0.96 | FOLH1 (0.54) | FOLH1GSTK1ENPEPLMNAANPEP | |
| SCHEMBL6809842 | 0.96 | GSTK1 (0.57) | FOLH1GSTK1ENPEPLMNAANPEP | |
| SCHEMBL21611884 | 0.96 | GSTK1 (0.57) | FOLH1GSTK1ENPEPLMNAANPEP | |
| SCHEMBL6805309 | 0.96 | GSTK1 (0.57) | FOLH1GSTK1ENPEPLMNAANPEP | |
| Dihydrolipoic Acid SCHEMBL19359055 | 0.96 | FOLH1 (0.54) | FOLH1GSTK1ENPEPLMNAANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100367949-C | Melanin extinguisher | OGA RES INC (JP) | 2008-02-13 | — | — | CN | claimed |
| US-20060122100-A1 | Melanin extinguisher | OGA RESEARCH, INCORPORATED (JP) | 2006-06-08 | — | — | US | claimed |
| CN-1681490-A | Melanin extinguisher | OGA RES INC (JP) | 2005-10-12 | — | — | CN | claimed |
| EP-1547590-A1 | MELANIN EXTINGUISHER | Oga Research, Incorporated (JP) | 2005-06-29 | — | — | EP | claimed |
| US-8048911-B2 | Melanin eliminator preparation | OGA Research, Inc. (JP) | 2011-11-01 | — | — | US | disclosed |
| US-20090093541-A1 | MELANIN ELIMINATOR PREPARATION | OGA RESEARCH, INC (JP) | 2009-04-09 | — | — | US | disclosed |
| CN-100367949-C | Melanin extinguisher | OGA RES INC (JP) | 2008-02-13 | — | — | CN | disclosed |
| JP-2006206561-A | STABILIZATION OF LIPOIC ACID DERIVATIVE-CONTAINING AQUEOUS PREPARATION | IWAKI KK | 2006-08-10 | — | — | JP | disclosed |
| US-20060122100-A1 | Melanin extinguisher | OGA RESEARCH, INCORPORATED (JP) | 2006-06-08 | — | — | US | disclosed |
| CN-1681490-A | Melanin extinguisher | OGA RES INC (JP) | 2005-10-12 | — | — | CN | disclosed |
| EP-1547590-A1 | MELANIN EXTINGUISHER | Oga Research, Incorporated (JP) | 2005-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122100-A1 | Melanin extinguisher | TYR, MC1R, MITF | FOLH1 3374/4885GSTK1 2911/4885ENPEP 314/4885 |
| US-20090093541-A1 | MELANIN ELIMINATOR PREPARATION | TYR, MC1R, MCHR1 | FOLH1 1909/4885GSTK1 3045/4885ENPEP 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.