Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18436536 | 0.81 | HSD17B10 (0.38) | HSD17B10ALDH1A1ALOX15TSHRALOX12 | |
| SCHEMBL24633233 | 0.73 | BACE1 (0.33) | — | |
| SCHEMBL23977356 | 0.69 | HSD17B10 (0.48) | HSD17B10ALDH1A1ALOX15TSHRALOX12 | |
| SCHEMBL25961944 | 0.69 | — | — | |
| SCHEMBL2350335 | 0.67 | LMNA (0.42) | ALDH1A1TSHRALOX12L3MBTL1POLB | |
| SCHEMBL22812572 | 0.67 | MAPT (0.36) | HSD17B10ALDH1A1ALOX15TSHRALOX12 | |
| SCHEMBL22756629 | 0.67 | MEN1 (0.31) | ALDH1A1ALOX15ALOX12L3MBTL1MEN1 | |
| SCHEMBL23584253 | 0.66 | CXCR2 (0.33) | HSD17B10ALDH1A1ALOX15TSHRALOX12 | |
| SCHEMBL8873990 | 0.65 | MMP2 (0.47) | ALDH1A1TSHRTDP1L3MBTL1POLB | |
| SCHEMBL21336458 | 0.65 | HSD17B10 (0.42) | HSD17B10ALDH1A1ALOX15TSHRALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3935129-B1 | LIGANDS FOR NANO-SIZED MATERIALS | MERCK PATENT GMBH (DE) | 2023-11-29 | — | — | EP | disclosed |
| EP-3762387-B1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-07-12 | — | — | EP | disclosed |