SCHEMBL2350335

SCHEMBL2350335

CC1(c2ccccc2)C=C1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.42
ALDH1A1 P00352 2/20 0.42
GAA P10253 2/20 0.42
MCL1 Q07820 2/20 0.42
PAX8 Q06710 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
OPRM1 P35372 1/20 0.40
OPRK1 P41145 1/20 0.40
OPRL1 P41146 1/20 0.40
TSHR P16473 1/20 0.35
ALOX12 P18054 1/20 0.35
ACHE P22303 1/20 0.35
APOBEC3A P31941 1/20 0.35
APOBEC3G Q9HC16 1/20 0.35
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MAOA P21397 2/20 0.33
MAOB P27338 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20240642 0.82 MMP2 (0.39) LMNAALDH1A1GAAMCL1PAX8
SCHEMBL12445313 0.82 MEN1 (0.33) LMNAALDH1A1GAAMCL1PAX8
SCHEMBL19936870 0.80 ALDH1A1 (0.34) LMNAALDH1A1GAAMCL1PAX8
SCHEMBL8873990 0.80 MMP2 (0.47) LMNAALDH1A1GAAMCL1PAX8
SCHEMBL23222658 0.78 ALDH1A1 (0.33) LMNAALDH1A1GAAMCL1PAX8
SCHEMBL9453683 0.75 ALDH1A1 (0.34) LMNAALDH1A1GAAMCL1PAX8
SCHEMBL5678989 0.75 ALDH1A1 (0.38) LMNAALDH1A1GAAMCL1PAX8
SCHEMBL14955087 0.74 HCAR2 (0.38) LMNAALDH1A1MEN1KMT2AHTT
SCHEMBL24633233 0.72 BACE1 (0.33)
SCHEMBL6152348 0.67 OPRM1 (0.38) ALDH1A1OPRM1OPRK1OPRL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119948008-A Method for preparing condensed ring aromatic amine by taking isonitrile and cyclopropene as raw materials 南方科技大学 2025-05-06 CN claimed
WO-2024011559-A1 FUSED AROMATIC AMINE PREPARING FROM ISOCYANIDE AND CYCLOPROPENE SOUTHERN UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2024-01-18 WO claimed
CN-114392291-A Folium artemisiae argyi burning backflow incense composition and preparation method and application thereof 黄山学院 2022-04-26 CN claimed
CN-108530389-B Preparation method of 2-aryl cyclopropylamine compound 东北师范大学 2020-06-09 CN claimed
CN-107488090-B Efficient catalytic asymmetric preparation method of N-cyclopropyl nitrone compound 东北师范大学 2020-06-02 CN claimed
CN-107522635-B N-cyclopropyl nitrone derivatives and preparation method thereof 东北师范大学 2020-02-14 CN claimed
CN-108530389-A A kind of preparation method of 2- aryl cyclopropyls amine compounds 东北师范大学 2018-09-14 CN claimed
CN-107522635-A A kind of N cyclopropyl nitrone derivative and preparation method thereof 东北师范大学 2017-12-29 CN claimed
CN-107488090-A A kind of efficient catalytic asymmetry preparation method of N cyclopropyl nitrone compound 东北师范大学 2017-12-19 CN claimed
EP-3164465-B1 IMPROVED PROCESSES FOR RECOVERING VALUABLE COMPONENTS FROM A CATALYTIC FAST PYROLYSIS PROCESS ANELLOTECH INC (US) 2025-10-29 EP disclosed
CN-114392291-A Folium artemisiae argyi burning backflow incense composition and preparation method and application thereof 黄山学院 2022-04-26 CN disclosed
US-10954452-B2 Processes for recovering valuable components from a catalytic fast pyrolysis process ANELLOTECH, INC. (US) 2021-03-23 US disclosed
CN-111777545-A Alkenyl cyclopropane indoline compound and preparation method thereof 南京工业大学 2020-10-16 CN disclosed
CN-108530389-B Preparation method of 2-aryl cyclopropylamine compound 东北师范大学 2020-06-09 CN disclosed
EP-1409440-A1 A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS ROHM AND HAAS COMPANY (US) 2004-04-21 EP disclosed
EP-1236397-B1 Delivery systems for cyclopropenes ROHM & HAAS (US) 2004-02-04 EP disclosed
US-6548448-B2 Delivery systems for cyclopropenes ROHM AND HAAS COMPANY 2003-04-15 US disclosed
US-20020198107-A1 Delivery systems for cyclopropenes AGROFRESH, INC. 2002-12-26 US disclosed
WO-2002068367-A1 A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS ROHM AND HAAS COMPANY (US) 2002-09-06 WO disclosed
EP-1236397-A2 Delivery systems for cyclopropenes ROHM AND HAAS COMPANY (US) 2002-09-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020198107-A1 Delivery systems for cyclopropenes FKBP2, FKBP4, FKBP1A LMNA 2716/4885ALDH1A1 1580/4885GAA 2868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.