Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24010241 | 0.83 | STAT3 (0.40) | RAB9AGAAPOLBHPGDL3MBTL1 | |
| SCHEMBL25822237 | 0.83 | LMNA (0.45) | NPC1RAB9ARXFP1MAPTTP53 | |
| SCHEMBL25822232 | 0.78 | RXFP1 (0.55) | RXFP1TP53SMN1; SMN2KDM4ELMNA | |
| SCHEMBL30290923 | 0.74 | DNMT1 (0.43) | MAPTGAAPOLBKDM4EALDH1A1 | |
| SCHEMBL24009942 | 0.74 | DNMT1 (0.43) | MAPTGAAPOLBKDM4EALDH1A1 | |
| SCHEMBL25827157 | 0.71 | HTR2C (0.40) | RAB9AGAATP53SMN1; SMN2 | |
| SCHEMBL7352861 | 0.71 | PDE4B (0.69) | MAPTGAASMN1; SMN2ATM | |
| SCHEMBL28989118 | 0.70 | ADRA2A (0.38) | MAPTSMN1; SMN2KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL7743046 | 0.69 | KMT2A (0.81) | NPC1RAB9AMAPTSMN1; SMN2POLB | |
| SCHEMBL25820804 | 0.69 | UCHL1 (0.45) | MAPTGAATP53SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | NPC1 901/4885RAB9A 1255/4885RXFP1 4004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.