Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | IDH2 | P48735 | 1/20 | 0.31 |
| ▸ | TLR4 | O00206 | 1/20 | 0.31 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3022736 | 0.84 | MAPT (0.38) | — | |
| SCHEMBL16970011 | 0.78 | TLR4 (0.35) | RIPK1PARP15PARP10PARP2TLR4 | |
| SCHEMBL4534691 | 0.78 | TDP1 (0.39) | RIPK1PARP15PARP10PARP2TLR4 | |
| SCHEMBL17046264 | 0.76 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL4689042 | 0.75 | PARP15 (0.37) | RIPK1PARP15PARP10PARP2TLR4 | |
| SCHEMBL4601200 | 0.74 | RIPK1 (0.36) | RIPK1PARP15PARP10PARP2TLR4 | |
| SCHEMBL27907014 | 0.73 | ALDH1A1 (0.31) | — | |
| SCHEMBL22587766 | 0.73 | ALDH1A1 (0.32) | — | |
| SCHEMBL17164203 | 0.72 | MCHR1 (0.38) | PARP15PARP10TLR4TLR2 | |
| SCHEMBL17164084 | 0.72 | MCHR1 (0.38) | PARP15PARP10PARP2TLR4TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382218-A1 | DELTA-5-DESATURASE INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2011-11-02 | — | — | EP | disclosed |