Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | G6PD | P11413 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3022736 | 0.87 | MAPT (0.38) | ALDH1A1MAPTKDM4EMEN1USP2 | |
| SCHEMBL17046264 | 0.79 | SMN1; SMN2 (0.33) | ALDH1A1MAPTKDM4EMEN1USP2 | |
| SCHEMBL28804105 | 0.78 | CYP2C19 (0.34) | ALDH1A1MAPTKDM4EMEN1USP2 | |
| SCHEMBL22587766 | 0.75 | ALDH1A1 (0.32) | ALDH1A1MAPTKDM4EMEN1USP2 | |
| SCHEMBL2582266 | 0.73 | RIPK1 (0.36) | — | |
| SCHEMBL27924972 | 0.69 | SLC2A1 (0.36) | L3MBTL1 | |
| SCHEMBL27907185 | 0.69 | LMNA (0.36) | KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL27907003 | 0.69 | — | — | |
| SCHEMBL3983109 | 0.67 | NUDT1 (0.36) | — | |
| SCHEMBL677491 | 0.67 | SCN4A (0.39) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103119043-A | Fused heterocyclic compound and use thereof | TAKEDA PHARMACEUTICAL | 2013-05-22 | — | — | CN | disclosed |