Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20113001 | 0.82 | ACHE (0.41) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL22343075 | 0.81 | ACHE (0.38) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL22570793 | 0.81 | ACHE (0.37) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL18137885 | 0.81 | ACHE (0.40) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL22342677 | 0.79 | ACHE (0.41) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL18083165 | 0.78 | DPP7 (0.36) | ACHE | |
| SCHEMBL22314737 | 0.76 | ACHE (0.35) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL19513091 | 0.76 | ACHE (0.58) | ACHE | |
| SCHEMBL23579337 | 0.76 | DDAH1 (0.43) | ACHE | |
| SCHEMBL15546760 | 0.76 | DDAH1 (0.43) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122750-A1 | CANCER COMBINATION THERAPY WITH IL-2 CONJUGATES AND CETUXIMAB | Synthorx, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |