⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25820610 | 0.92 | ACHE (0.33) | — | |
| SCHEMBL25822328 | 0.90 | — | — | |
| SCHEMBL25820450 | 0.90 | ACHE (0.32) | — | |
| SCHEMBL25822259 | 0.85 | — | — | |
| SCHEMBL21981176 | 0.82 | CYP4F2 (0.31) | — | |
| SCHEMBL25820461 | 0.82 | HTR2C (0.31) | — | |
| SCHEMBL25822772 | 0.81 | ACHE (0.31) | — | |
| SCHEMBL17532406 | 0.78 | ACHE (0.32) | — | |
| SCHEMBL25822261 | 0.75 | PAOX (0.32) | — | |
| SCHEMBL20892164 | 0.72 | DNM1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11697804-B2 | Transcriptionally targeted and CpG-free plasmid for theranostic gene therapy | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-07-11 | — | — | US | disclosed |