Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25820610 | 0.98 | ACHE (0.33) | ACHEHTR2C | |
| SCHEMBL25822839 | 0.90 | — | — | |
| SCHEMBL25822259 | 0.90 | — | — | |
| SCHEMBL21981176 | 0.87 | CYP4F2 (0.31) | — | |
| SCHEMBL25820461 | 0.87 | HTR2C (0.31) | HTR2C | |
| SCHEMBL17532406 | 0.83 | ACHE (0.32) | ACHEHTR2C | |
| SCHEMBL25822328 | 0.81 | — | — | |
| SCHEMBL20892164 | 0.76 | DNM1 (0.35) | ACHEHTR2C | |
| SCHEMBL25822257 | 0.74 | ACHE (0.35) | ACHEHTR2C | |
| SCHEMBL25820454 | 0.74 | ACHE (0.35) | ACHEHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11697804-B2 | Transcriptionally targeted and CpG-free plasmid for theranostic gene therapy | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11697804-B2 | Transcriptionally targeted and CpG-free plasmid for theranostic gene therapy | POLRMT, HDGF, PCNP | ACHE 4870/4885HTR2C 4454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.