SCHEMBL25822932

SCHEMBL25822932

Cc1csc2ccnc(Br)c12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDR P35968 10/20 0.37
AURKA O14965 3/20 0.37
AURKB Q96GD4 3/20 0.37
PLK4 O00444 2/20 0.32
ROCK2 O75116 2/20 0.32
RPS6KA5 O75582 2/20 0.32
PRKD3 O94806 2/20 0.32
MAP4K4 O95819 2/20 0.32
LCK P06239 2/20 0.32
CSF1R P07333 2/20 0.32
LYN P07948 2/20 0.32
RET P07949 2/20 0.32
KIT P10721 2/20 0.32
FGFR1 P11362 2/20 0.32
FLT1 P17948 2/20 0.32
RPS6KB1 P23443 2/20 0.32
EPHA2 P29317 2/20 0.32
AXL P30530 2/20 0.32
FLT3 P36888 2/20 0.32
FRK P42685 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18341971 0.82 KDR (0.40) KDRAURKAAURKBPLK4ROCK2
SCHEMBL8284990 0.77 KDR (0.56) KDRAURKAAURKBPLK4ROCK2
SCHEMBL13764546 0.77 KDR (0.40) KDRAURKAAURKBPLK4ROCK2
SCHEMBL4426300 0.71 CYP2A6 (0.46) CYP2A6PIP4K2C
SCHEMBL27405450 0.70 LRRK2 (0.48) KDRAURKAAURKBFLT3PIP4K2C
SCHEMBL4764241 0.69 KDR (0.40) KDRAURKAAURKBPLK4ROCK2
SCHEMBL1899302 0.69 MRGPRX1 (0.38) IRAK4PIP4K2C
SCHEMBL25822955 0.69 CCR1 (0.33) CYP2A6
SCHEMBL2088114 0.68 CA2 (0.44) CYP2A6
SCHEMBL3785902 0.67 CSNK2A1 (0.37) KDRAURKAAURKBEPHB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230209989-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209989-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230209989-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME DDT, L3MBTL1, LAGE3 KDR 2314/4885AURKA 1621/4885AURKB 2460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.