Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 5/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24675646 | 1.00 | PLA2G4B (0.48) | PLA2G4BMMP9MMP8MMP13TSHR | |
| SCHEMBL24675644 | 1.00 | PLA2G4B (0.48) | PLA2G4BMMP9MMP8MMP13TSHR | |
| SCHEMBL24675241 | 0.87 | PPARD (0.42) | PLA2G4BMMP9MMP8MMP13POLB | |
| SCHEMBL24675242 | 0.87 | PPARD (0.42) | PLA2G4BMMP9MMP8MMP13POLB | |
| SCHEMBL25823404 | 0.87 | PPARD (0.42) | PLA2G4BMMP9MMP8MMP13POLB | |
| SCHEMBL24675711 | 0.86 | PLA2G4B (0.52) | PLA2G4BMMP9MMP8MMP13POLB | |
| SCHEMBL18591857 | 0.86 | ALDH1A1 (0.51) | PLA2G4BTSHRALDH1A1POLBTDP1 | |
| Hydrochloric Acid SCHEMBL30491000 | 0.85 | PLA2G4B (0.53) | PLA2G4BMMP9MMP8MMP13POLB | |
| Hydrochloric Acid SCHEMBL30490834 | 0.85 | PLA2G4B (0.53) | PLA2G4BMMP9MMP8MMP13POLB | |
| SCHEMBL24675626 | 0.85 | SMN1; SMN2 (0.49) | PLA2G4BALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129564-A1 | DEGRADERS OF GRK2 AND USES THEREOF | CYGNAL THERAPEUTICS, INC. (US) | 2023-07-06 | — | — | WO | disclosed |