Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24675241 | 1.00 | PPARD (0.42) | PPARDPLA2G4BLMNAMMP9MMP8 | |
| SCHEMBL24675242 | 1.00 | PPARD (0.42) | PPARDPLA2G4BLMNAMMP9MMP8 | |
| SCHEMBL24675709 | 0.87 | HPGD (0.43) | PLA2G4BLMNAMMP9MMP8MMP13 | |
| SCHEMBL24675229 | 0.87 | LMNA (0.41) | PLA2G4BLMNAMMP9MMP8MMP13 | |
| SCHEMBL24675703 | 0.87 | HPGD (0.43) | PLA2G4BLMNAMMP9MMP8MMP13 | |
| SCHEMBL24675644 | 0.87 | PLA2G4B (0.48) | PLA2G4BLMNAMMP9MMP8MMP13 | |
| SCHEMBL25823398 | 0.87 | PLA2G4B (0.48) | PLA2G4BLMNAMMP9MMP8MMP13 | |
| SCHEMBL24675646 | 0.87 | PLA2G4B (0.48) | PLA2G4BLMNAMMP9MMP8MMP13 | |
| SCHEMBL24675798 | 0.85 | KDM4E (0.45) | LMNAMEN1KMT2A | |
| SCHEMBL24675470 | 0.85 | KDM4E (0.45) | LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129564-A1 | DEGRADERS OF GRK2 AND USES THEREOF | CYGNAL THERAPEUTICS, INC. (US) | 2023-07-06 | — | — | WO | disclosed |