Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 3/20 | 0.48 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25825938 | 0.92 | SLC22A12 (0.46) | CHRM2CHRM1CHRM3BCHENOS1 | |
| SCHEMBL4568933 | 0.85 | PPARA (0.50) | BCHESMN1; SMN2CYP4F2CYP4A11NR1H4 | |
| SCHEMBL11464993 | 0.83 | BCHE (0.68) | CHRM2CHRM1CHRM3BCHENOS1 | |
| SCHEMBL2204528 | 0.82 | SMN1; SMN2 (0.46) | BCHETAAR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14855263 | 0.80 | CHRM2 (0.57) | CHRM2CHRM1CHRM3BCHEMEN1 | |
| SCHEMBL25823623 | 0.79 | BCHE (0.42) | BCHEMTNR1AMTNR1B | |
| SCHEMBL12110018 | 0.78 | SOD1 (0.52) | BCHESMN1; SMN2CYP4F2CYP4A11NR1H4 | |
| SCHEMBL27945322 | 0.77 | SMN1; SMN2 (0.47) | BCHESMN1; SMN2CYP4F2CYP4A11NR1H4 | |
| SCHEMBL12377082 | 0.77 | CHRM2 (0.54) | CHRM2CHRM1CHRM3MEN1KMT2A | |
| SCHEMBL25819935 | 0.77 | MEN1 (0.62) | CHRM2CHRM1CHRM3BCHETAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | CHRM2 2420/4885CHRM1 3108/4885CHRM3 1218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.